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Crebl2 regulates cell metabolism in muscle and liver cells

We previously identified Drosophila REPTOR and REPTOR-BP as transcription factors downstream of mTORC1 that play an important role in regulating organismal metabolism. We study here the mammalian ortholog of REPTOR-BP, Crebl2. We find that Crebl2 mediates part of the transcriptional induction caused...

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Detalles Bibliográficos
Autores principales: Tiebe, Marcel, Lutz, Marilena, Senyilmaz Tiebe, Deniz, Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934747/
https://www.ncbi.nlm.nih.gov/pubmed/31882710
http://dx.doi.org/10.1038/s41598-019-56407-w