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Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH
Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunction at early stages of the disease. Our aim was to c...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934751/ https://www.ncbi.nlm.nih.gov/pubmed/31882668 http://dx.doi.org/10.1038/s41598-019-56366-2 |