9-ING-41, a small molecule inhibitor of GSK-3beta, potentiates the effects of anticancer therapeutics in bladder cancer

Glycogen synthase kinase-3 beta (GSK-3β), a serine/threonine kinase, has been identified as a potential therapeutic target in human bladder cancer. In the present study, we investigated the antitumor effect of a small molecule GSK-3β inhibitor, 9-ING-41, currently in clinical studies in patients wit...

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Detalles Bibliográficos
Autores principales: Kuroki, Hiroo, Anraku, Tsutomu, Kazama, Akira, Bilim, Vladimir, Tasaki, Masayuki, Schmitt, Daniel, Mazar, Andrew P., Giles, Francis J, Ugolkov, Andrey, Tomita, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934761/
https://www.ncbi.nlm.nih.gov/pubmed/31882719
http://dx.doi.org/10.1038/s41598-019-56461-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934761/
https://www.ncbi.nlm.nih.gov/pubmed/31882719
http://dx.doi.org/10.1038/s41598-019-56461-4

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