Cargando…

The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis

Aberrant expression of the Spectraplakin Dystonin (DST) has been observed in various cancers, including those of the breast. However, little is known about its role in carcinogenesis. In this report, we demonstrate that Dystonin is a candidate tumour suppressor in breast cancer and provide an underl...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Praachi B., Guerreiro, Patrícia S., Canato, Sara, Janody, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934804/
https://www.ncbi.nlm.nih.gov/pubmed/31882643
http://dx.doi.org/10.1038/s41598-019-56296-z