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Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches
The 2,5-Diketopiperazines (DKPs) constitute a large family of natural products with important biological activities. Bicyclomycin is a clinically-relevant DKP antibiotic that is the first and only member in a class known to target the bacterial transcription termination factor Rho. It derives from c...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934819/ https://www.ncbi.nlm.nih.gov/pubmed/31882990 http://dx.doi.org/10.1038/s41598-019-56747-7 |