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Patient-Derived Cells to Guide Targeted Therapy for Advanced Lung Adenocarcinoma
Adequate preclinical model and model establishment procedure are required to accelerate translational research in lung cancer. We streamlined a protocol for establishing patient-derived cells (PDC) and identified effective targeted therapies and novel resistance mechanisms using PDCs. We generated 2...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934824/ https://www.ncbi.nlm.nih.gov/pubmed/31882684 http://dx.doi.org/10.1038/s41598-019-56356-4 |