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ONECUT2 overexpression promotes RAS-driven lung adenocarcinoma progression

Aberrant differentiation, driven by activation of normally silent tissue-specific genes, results in a switch of cell identity and often leads to cancer progression. The underlying genetic and epigenetic events are largely unexplored. Here, we report ectopic activation of the hepatobiliary-, intestin...

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Detalles Bibliográficos
Autores principales: Ma, Qingyang, Wu, Kai, Li, Hui, Li, Huichun, Zhu, Yufei, Hu, Guohong, Hu, Landian, Kong, Xiangyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934839/
https://www.ncbi.nlm.nih.gov/pubmed/31882655
http://dx.doi.org/10.1038/s41598-019-56277-2