Evolutionary Analysis of Bile Acid-Conjugating Enzymes Reveals a Complex Duplication and Reciprocal Loss History

To fulfill their physiological functions, bile acids are conjugated with amino acids. In humans, conjugation is catalyzed by bile acid coenzyme A: amino acid N-acyltransferase (BAAT), an enzyme with a highly conserved catalytic triad in its active site. Interestingly, the conjugated amino acids are...

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Detalles Bibliográficos
Autores principales: Kirilenko, Bogdan M, Hagey, Lee R, Barnes, Stephen, Falany, Charles N, Hiller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934887/
https://www.ncbi.nlm.nih.gov/pubmed/31670760
http://dx.doi.org/10.1093/gbe/evz238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934887/
https://www.ncbi.nlm.nih.gov/pubmed/31670760
http://dx.doi.org/10.1093/gbe/evz238

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