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Efficient Synthesis of Norbuprenorphines Coupled with Enkephalins and Investigation of Their Permeability

An efficient approach for the synthesis of norbuprenorphin derivatives through coupling of enkephalins and norbuprenorphine intermediates is described. Norbuprenorphine derivative was synthesized from thebaine and then, its reaction with succinic acid and phthalic acid was also studied. Meanwhile, t...

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Detalles Bibliográficos
Autores principales: Balalaie, Saeed, Malakoutikhah, Morteza, Teixidó, Meritxell, Fathi Vavsari, Vaezeh, Giralt, Ernest, Haghighatnia, Yaghoub, Hamdan, Fatima, Arabanian, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934973/
https://www.ncbi.nlm.nih.gov/pubmed/32641938
http://dx.doi.org/10.22037/ijpr.2019.14712.12602