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Synthesis and Biological Assessment of 2-Hydroxyiminoethanones as Anti-Inflammatory and β-Amyloid Aggregation Inhibitors

Alzheimer’s disease (AD) is a neuroinflammatory based pathologic state in which β-amyloid aggregates are major devastating agents. In this study, a series of 2-hydroxyiminoethanones were synthesized and evaluated as anti-inflammatory in carrageenan and formalin tests and inhibitors of β-amyloid aggr...

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Detalles Bibliográficos
Autores principales: Valipour, Mehdi, Davaji, Issa, Abedi, Niusha, Rajabi, Mahsa, Küçükkılınç, Tuba Tüylü, Ayazgök, Beyza, Irannejad, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934981/
https://www.ncbi.nlm.nih.gov/pubmed/32641939
http://dx.doi.org/10.22037/ijpr.2019.15567.13181