Cargando…

Synthesis and Biological Assessment of 2-Hydroxyiminoethanones as Anti-Inflammatory and β-Amyloid Aggregation Inhibitors

Alzheimer’s disease (AD) is a neuroinflammatory based pathologic state in which β-amyloid aggregates are major devastating agents. In this study, a series of 2-hydroxyiminoethanones were synthesized and evaluated as anti-inflammatory in carrageenan and formalin tests and inhibitors of β-amyloid aggr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valipour, Mehdi, Davaji, Issa, Abedi, Niusha, Rajabi, Mahsa, Küçükkılınç, Tuba Tüylü, Ayazgök, Beyza, Irannejad, Hamid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934981/ https://www.ncbi.nlm.nih.gov/pubmed/32641939 http://dx.doi.org/10.22037/ijpr.2019.15567.13181

Ejemplares similares

Synthesis of New 3-Arylcoumarins Bearing N-Benzyl Triazole Moiety: Dual Lipoxygenase and Butyrylcholinesterase Inhibitors With Anti-Amyloid Aggregation and Neuroprotective Properties Against Alzheimer’s Disease
por: Pourabdi, Ladan, et al.
Publicado: (2022)

Design, synthesis, and biological evaluation of new 2-(4-(methylsulfonyl)phenyl)-N-phenylimidazo[1,2-a]pyridin-3-amine as selective COX-2 inhibitors
por: Movahed, Mahsa Azami, et al.
Publicado: (2023)

Novel Coumarin–Pyridine Hybrids as Potent Multi-Target Directed Ligands Aiming at Symptoms of Alzheimer’s Disease
por: Babaei, Elaheh, et al.
Publicado: (2022)

Therapeutic potential of chelerythrine as a multi-purpose adjuvant for the treatment of COVID-19
por: Valipour, Mehdi, et al.
Publicado: (2021)

Discovery of Chalcone-Based Hybrid Structures as High Affinity and Site-Specific Inhibitors against SARS-CoV-2: A Comprehensive Structural Analysis Based on Various Host-Based and Viral Targets
por: Valipour, Mehdi, et al.
Publicado: (2023)

Benzoindolizidine Alkaloids Tylophorine and Lycorine and Their Analogues with Antiviral, Anti-Inflammatory, and Anticancer Properties: Promises and Challenges
por: Di Sotto, Antonella, et al.
Publicado: (2023)

Bis(methanol-κO)bis(1,2-diamino-2-hydroxyiminoethanone oximato-κ(2) N,N′)copper(II) bis(oxamide dioxime) methanol disolvate
por: Liu, Daying, et al.
Publicado: (2012)

Detection and Endodontic Treatment of Unusual Anatomic Variations in Second Premolars: A Case Report
por: Davaji, Mina, et al.
Publicado: (2023)

Amyloids and protein aggregation
por: Linse, Sara, et al.
Publicado: (2023)

Misfolding and Amyloid Aggregation of Apomyoglobin
por: Iannuzzi, Clara, et al.
Publicado: (2013)

The yin and yang of amyloid aggregation
por: Falsone, S Fabio
Publicado: (2015)

Structure and Aggregation Mechanisms in Amyloids
por: L. Almeida, Zaida, et al.
Publicado: (2020)

Natural Inhibitors of Amyloid Aggregation
por: Tortora, Paolo, et al.
Publicado: (2023)

Multicomponent Synthesis of Polyphenols and Their In Vitro Evaluation as Potential β-Amyloid Aggregation Inhibitors
por: Galante, Denise, et al.
Publicado: (2019)

Synthesis, in vitro antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones
por: Ayati, Adile, et al.
Publicado: (2012)

Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity
por: Cheng, Pin-Nan, et al.
Publicado: (2012)

Bleomycin modulates amyloid aggregation in β-amyloid and hIAPP
por: Kumari, Anchala, et al.
Publicado: (2020)

Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation
por: Groh, Nicole, et al.
Publicado: (2017)

Short Peptides as Inhibitors of Amyloid Aggregation
por: Neddenriep, Bradley, et al.
Publicado: (2011)

Assembly Mechanism for Aggregation of Amyloid Fibrils
por: Zhang, Lingyun
Publicado: (2018)

The amyloid interactome: Exploring protein aggregation
por: Biza, Konstantina V., et al.
Publicado: (2017)

Food protein-derived amyloids do not accelerate amyloid β aggregation
por: Rahman, M. Mahafuzur, et al.
Publicado: (2023)

Exploring New Biological Functions of Amyloids: Bacteria Cell Agglutination Mediated by Host Protein Aggregation
por: Torrent, Marc, et al.
Publicado: (2012)

Design and Synthesis of 6‐O‐Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid β Aggregation
por: Uchimura, Kenji, et al.
Publicado: (2022)

Monitoring Alzheimer Amyloid Peptide Aggregation by EPR
por: Sepkhanova, I., et al.
Publicado: (2009)

Tau aggregation and its interplay with amyloid-β
por: Nisbet, Rebecca M., et al.
Publicado: (2014)

Mechanisms for the inhibition of amyloid aggregation by small ligands
por: Ramazzotti, Matteo, et al.
Publicado: (2016)

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms
por: Giorgetti, Sofia, et al.
Publicado: (2018)

Ultrasonic Characterization of Amyloid-Like Ovalbumin Aggregation
por: Jansens, Koen J. A., et al.
Publicado: (2017)

The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity
por: Iannuzzi, Clara, et al.
Publicado: (2015)

The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity
por: Porter, Tenielle, et al.
Publicado: (2016)

Nanomaterials for Modulating the Aggregation of β-Amyloid Peptides
por: Huang, Yaliang, et al.
Publicado: (2021)

Magnetoelectric dissociation of Alzheimer’s β-amyloid aggregates
por: Jang, Jinhyeong, et al.
Publicado: (2022)

Key Residue for Aggregation of Amyloid-β Peptides
por: Itoh, Satoru G., et al.
Publicado: (2022)

The influence of cations on α-lactalbumin amyloid aggregation
por: Antosova, Andrea, et al.
Publicado: (2022)

Small molecules to target tau amyloid aggregation
por: Manglano-Artuñedo, Zoe, et al.
Publicado: (2023)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
por: Fan, Yujuan, et al.
Publicado: (2017)

The Effect of Nanoparticles on Amyloid Aggregation Depends on the Protein Stability and Intrinsic Aggregation Rate
por: Cabaleiro-Lago, C., et al.
Publicado: (2011)

Patterning amyloid-β aggregation under the effect of acetylcholinesterase using a biological nanopore - an in vitro study
por: Subramanian, Nandhini, et al.
Publicado: (2023)

Preparation of Diaminedicarboxyplatinum (II) Functionalized Single-Wall Carbon Nanotube via Bingel Reaction as a Novel Cytotoxic Agent
por: Irannejad, Saeed, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ieiuvvcqhe5s2licho0i78rhdk