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Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways

Trehalose, as a natural disaccharide, is known as an autophagy inducer. The neuroprotective effects of trehalose in the rat model of Parkinson′s disease were the aim of the present study. Parkinson′s disease model was induced by injecting 6-hydroxydopamine (6-OHDA) in the striatum of male Wistar rat...

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Detalles Bibliográficos
Autores principales: Darabi, Shahram, Noori-Zadeh, Ali, Abbaszadeh, Hojjat-Allah, Rajaei, Farzad, Bakhtiyari, Salar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934986/
https://www.ncbi.nlm.nih.gov/pubmed/32641951
http://dx.doi.org/10.22037/ijpr.2019.2387