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Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways
Trehalose, as a natural disaccharide, is known as an autophagy inducer. The neuroprotective effects of trehalose in the rat model of Parkinson′s disease were the aim of the present study. Parkinson′s disease model was induced by injecting 6-hydroxydopamine (6-OHDA) in the striatum of male Wistar rat...
Autores principales: | Darabi, Shahram, Noori-Zadeh, Ali, Abbaszadeh, Hojjat-Allah, Rajaei, Farzad, Bakhtiyari, Salar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934986/ https://www.ncbi.nlm.nih.gov/pubmed/32641951 http://dx.doi.org/10.22037/ijpr.2019.2387 |
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