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ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia

Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary epithelia are associated with dysregulated Wnt/β-catenin signaling in chronic airway diseases, but underlying mechanisms remain elusive, and studies yield seemingly contradict...

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Detalles Bibliográficos
Autores principales: Haas, Maximilian, Vázquez, José Luis Gómez, Sun, Dingyuan Iris, Tran, Hong Thi, Brislinger, Magdalena, Tasca, Alexia, Shomroni, Orr, Vleminckx, Kris, Walentek, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935018/
https://www.ncbi.nlm.nih.gov/pubmed/31553905
http://dx.doi.org/10.1016/j.celrep.2019.08.063