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Approaching the challenges of MKK3/p38delta MAPK targeting for therapeutic purpose in colorectal cancer
MKK3 is a member of the dual specificity kinase group specific upstream activator of p38 MAPK proteins. We originally identified MKK3 as mutant p53 (mutp53) gain-of-function (GOF) upregulated target gene in different tumor models. To deeply investigate the MKK3 functions in cancer, taking advantage...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935053/ https://www.ncbi.nlm.nih.gov/pubmed/31881903 http://dx.doi.org/10.1186/s13046-019-1513-4 |