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Approaching the challenges of MKK3/p38delta MAPK targeting for therapeutic purpose in colorectal cancer

MKK3 is a member of the dual specificity kinase group specific upstream activator of p38 MAPK proteins. We originally identified MKK3 as mutant p53 (mutp53) gain-of-function (GOF) upregulated target gene in different tumor models. To deeply investigate the MKK3 functions in cancer, taking advantage...

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Detalles Bibliográficos
Autores principales:	Stramucci, Lorenzo, Bossi, Gianluca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935053/ https://www.ncbi.nlm.nih.gov/pubmed/31881903 http://dx.doi.org/10.1186/s13046-019-1513-4

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