The let-7 family of microRNAs suppresses immune evasion in head and neck squamous cell carcinoma by promoting PD-L1 degradation

BACKGROUND: Accumulation of immunosuppressive protein programmed death-ligand 1 (PD-L1) has been documented in several cancers and contributes to the evasion of the host immune system. However, cancer cell-intrinsic signaling-dependent control of PD-L1 expression remains to be elucidated. Herein, we...

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Detalles Bibliográficos
Autores principales: Yu, Dan, Liu, Xueshibojie, Han, Guanghong, Liu, Yan, Zhao, Xue, Wang, Di, Bian, Xiaomin, Gu, Tingting, Wen, Lianji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935121/
https://www.ncbi.nlm.nih.gov/pubmed/31881947
http://dx.doi.org/10.1186/s12964-019-0490-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935121/
https://www.ncbi.nlm.nih.gov/pubmed/31881947
http://dx.doi.org/10.1186/s12964-019-0490-8

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