Cargando…

BAP31 regulates IRAK1-dependent neuroinflammation in microglia

BACKGROUND: Microglia, the mononuclear immune cells of the central nervous system (CNS), are essential for the maintenance of CNS homeostasis. BAP31, a resident and ubiquitously expressed protein of the endoplasmic reticulum, serves as a sorting factor for its client proteins, mediating the subseque...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xia, Jiao, Kun, Jia, Cong-cong, Li, Guo-xun, Yuan, Qing, Xu, Ji-kai, Hou, Yue, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935200/
https://www.ncbi.nlm.nih.gov/pubmed/31883536
http://dx.doi.org/10.1186/s12974-019-1661-7