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miR-149 inhibits cell proliferation and enhances chemosensitivity by targeting CDC42 and BCL2 in neuroblastoma

BACKGROUND: Neuroblastoma (NB) is one of most common childhood tumors with high mortality among children worldwide. microRNAs (miRNAs) have been reported to play essential roles in the pathogenesis and therapeutics of NB. However, the role of miR-149 and its mechanism remain poorly understood. MAIN...

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Detalles Bibliográficos
Autores principales: Mao, Fengxia, Zhang, Ju, Cheng, Xinru, Xu, Qianya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935209/
https://www.ncbi.nlm.nih.gov/pubmed/31889909
http://dx.doi.org/10.1186/s12935-019-1082-9