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The history of neuromyelitis optica. Part 2: ‘Spinal amaurosis’, or how it all began
Neuromyelitis optica (NMO) was long considered a clinical variant of multiple sclerosis (MS). However, the discovery of a novel and pathogenic anti-astrocytic serum autoantibody targeting aquaporin-4 (termed NMO-IgG or AQP4-Ab), the most abundant water channel protein in the central nervous system,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935230/ https://www.ncbi.nlm.nih.gov/pubmed/31883522 http://dx.doi.org/10.1186/s12974-019-1594-1 |