Complement factor H contributes to mortality in humans and mice with bacterial meningitis

BACKGROUND: The complement system is a vital component of the inflammatory response occurring during bacterial meningitis. Blocking the complement system was shown to improve the outcome of experimental pneumococcal meningitis. Complement factor H (FH) is a complement regulatory protein inhibiting a...

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Detalles Bibliográficos
Autores principales: Kasanmoentalib, E. Soemirien, Valls Serón, Mercedes, Engelen-Lee, Joo Yeon, Tanck, Michael W., Pouw, Richard B., van Mierlo, Gerard, Wouters, Diana, Pickering, Matthew C., van der Ende, Arie, Kuijpers, Taco W., Brouwer, Matthijs C., van de Beek, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935240/
https://www.ncbi.nlm.nih.gov/pubmed/31883521
http://dx.doi.org/10.1186/s12974-019-1675-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935240/
https://www.ncbi.nlm.nih.gov/pubmed/31883521
http://dx.doi.org/10.1186/s12974-019-1675-1

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