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ki67 nuclei detection and ki67-index estimation: a novel automatic approach based on human vision modeling
BACKGROUND: The protein ki67 (pki67) is a marker of tumor aggressiveness, and its expression has been proven to be useful in the prognostic and predictive evaluation of several types of tumors. To numerically quantify the pki67 presence in cancerous tissue areas, pathologists generally analyze histo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935242/ https://www.ncbi.nlm.nih.gov/pubmed/31881821 http://dx.doi.org/10.1186/s12859-019-3285-4 |