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Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models

BACKGROUND: Few chemotherapies are available for neuroendocrine tumors, especially for highly malignant neuroendocrine cancers. The third-generation oncolytic herpes simplex virus type 1 (HSV-1) T-01 selectively replicates in tumor cells and shows cytotoxicity against tumor cells without damaging su...

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Detalles Bibliográficos
Autores principales: Matsushima, Hideyuki, Kaibori, Masaki, Hatta, Masahiko, Ishizaki, Morihiko, Nakatake, Richi, Okumura, Tadayoshi, Yoshii, Kengo, Todo, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935252/
https://www.ncbi.nlm.nih.gov/pubmed/31903171
http://dx.doi.org/10.18632/oncotarget.27391