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Berbamine Enhances the Efficacy of Gefitinib by Suppressing STAT3 Signaling in Pancreatic Cancer Cells

BACKGROUND: Small molecular inhibitors such as gefitinib (Gefi), which target EGF receptor (EGFR), are considered to be a viable pathway for the selective inhibition of pancreatic cancer (PC) development. However, the large difference in Gefi response between PC patient individuals and PC cell lines...

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Detalles Bibliográficos
Autores principales: Hu, Bingren, Cai, Huajie, Yang, Shouzhang, Tu, Jinfu, Huang, Xiaming, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935307/
https://www.ncbi.nlm.nih.gov/pubmed/31920333
http://dx.doi.org/10.2147/OTT.S223242