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Combination of STING Pathway Agonist With Saponin Is an Effective Adjuvant in Immunosenescent Mice

There is an urgent need to improve protective responses to influenza vaccination in the elderly population, which is at especially high risk for adverse outcomes from influenza infection. Currently available inactivated vaccines provide limited protection, even when a 4-fold higher dose of the vacci...

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Detalles Bibliográficos
Autores principales: Vassilieva, Elena V., Taylor, Dahnide W., Compans, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935580/
https://www.ncbi.nlm.nih.gov/pubmed/31921219
http://dx.doi.org/10.3389/fimmu.2019.03006