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Denosumab-induced hypocalcaemia in metastatic castrate-resistant prostate cancer

SUMMARY: Denosumab is a fully human MAB that acts as a potent anti-resorptive by inhibiting activation of osteoclasts by inhibiting the receptor activator of nuclear factor-kappa B (RANK) ligand. Hypocalcaemia has been reported as one of the serious adverse sequelae of use of denosumab. We present a...

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Detalles Bibliográficos
Autores principales: Gunawan, Florence, George, Elizabeth, Kotowicz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935716/
https://www.ncbi.nlm.nih.gov/pubmed/31829971
http://dx.doi.org/10.1530/EDM-19-0063