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Free-energy-based framework for early forecasting of stem cell differentiation

Commitment of stem cells to different lineages is inherently stochastic but regulated by a range of environmental bio/chemo/mechanical cues. Here, we develop an integrated stochastic modelling framework for predicting the differentiation of hMSCs in response to a range of environmental cues, includi...

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Detalles Bibliográficos
Autores principales: Suresh, H., Shishvan, S. S., Vigliotti, A., Deshpande, V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936038/
https://www.ncbi.nlm.nih.gov/pubmed/31847759
http://dx.doi.org/10.1098/rsif.2019.0571