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Clonal reconstruction from time course genomic sequencing data
BACKGROUND: Bacterial cells during many replication cycles accumulate spontaneous mutations, which result in the birth of novel clones. As a result of this clonal expansion, an evolving bacterial population has different clonal composition over time, as revealed in the long-term evolution experiment...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936074/ https://www.ncbi.nlm.nih.gov/pubmed/31888455 http://dx.doi.org/10.1186/s12864-019-6328-3 |