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Clonal reconstruction from time course genomic sequencing data

BACKGROUND: Bacterial cells during many replication cycles accumulate spontaneous mutations, which result in the birth of novel clones. As a result of this clonal expansion, an evolving bacterial population has different clonal composition over time, as revealed in the long-term evolution experiment...

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Detalles Bibliográficos
Autores principales: Ismail, Wazim Mohammed, Tang, Haixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936074/
https://www.ncbi.nlm.nih.gov/pubmed/31888455
http://dx.doi.org/10.1186/s12864-019-6328-3