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Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells

[Image: see text] Retinaldehyde dehydrogenases belong to a superfamily of enzymes that regulate cell differentiation and are responsible for detoxification of anticancer drugs. Chemical tools and methods are of great utility to visualize and quantify aldehyde dehydrogenase (ALDH) activity in health...

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Detalles Bibliográficos
Autores principales: Koenders, Sebastiaan T. A., Wijaya, Lukas S., Erkelens, Martje N., Bakker, Alexander T., van der Noord, Vera E., van Rooden, Eva J., Burggraaff, Lindsey, Putter, Pasquale C., Botter, Else, Wals, Kim, van den Elst, Hans, den Dulk, Hans, Florea, Bogdan I., van de Water, Bob, van Westen, Gerard J. P., Mebius, Reina E., Overkleeft, Herman S., Le Dévédec, Sylvia E., van der Stelt, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936097/
https://www.ncbi.nlm.nih.gov/pubmed/31893226
http://dx.doi.org/10.1021/acscentsci.9b01022