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Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells
[Image: see text] Retinaldehyde dehydrogenases belong to a superfamily of enzymes that regulate cell differentiation and are responsible for detoxification of anticancer drugs. Chemical tools and methods are of great utility to visualize and quantify aldehyde dehydrogenase (ALDH) activity in health...
Autores principales: | Koenders, Sebastiaan T. A., Wijaya, Lukas S., Erkelens, Martje N., Bakker, Alexander T., van der Noord, Vera E., van Rooden, Eva J., Burggraaff, Lindsey, Putter, Pasquale C., Botter, Else, Wals, Kim, van den Elst, Hans, den Dulk, Hans, Florea, Bogdan I., van de Water, Bob, van Westen, Gerard J. P., Mebius, Reina E., Overkleeft, Herman S., Le Dévédec, Sylvia E., van der Stelt, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936097/ https://www.ncbi.nlm.nih.gov/pubmed/31893226 http://dx.doi.org/10.1021/acscentsci.9b01022 |
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