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Cellular and molecular characterization of multiplex autism in human induced pluripotent stem cell-derived neurons
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with pronounced heritability in the general population. This is largely attributable to the effects of polygenic susceptibility, with inherited liability exhibiting distinct sex differences in phenotypic expression. Attempts...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936127/ https://www.ncbi.nlm.nih.gov/pubmed/31893020 http://dx.doi.org/10.1186/s13229-019-0306-0 |