PADI3 induces cell cycle arrest via the Sirt2/AKT/p21 pathway and acts as a tumor suppressor gene in colon cancer

OBJECTIVE: As a member of the peptidyl arginine deiminase (PAD) family, PADI3 is weakly expressed in colon cancer tissues and highly expressed in adjacent colon cancer tissues. However, the role of PADI3 in colon cancer is unclear. In this study, we investigated the function and molecular mechanism...

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Detalles Bibliográficos
Autores principales: Chang, Xiaotian, Chai, Zhengbin, Zou, Jiaorui, Wang, Hongxing, Wang, Yao, Zheng, Yabing, Wu, Hui, Liu, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936227/
https://www.ncbi.nlm.nih.gov/pubmed/31908891
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936227/
https://www.ncbi.nlm.nih.gov/pubmed/31908891
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0065

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