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Localized accumulation of Xist RNA in X chromosome inactivation
The non-coding RNA Xist regulates the process of X chromosome inactivation, in which one of the two X chromosomes present in cells of early female mammalian embryos is selectively and coordinately shut down. Remarkably Xist RNA functions in cis, affecting only the chromosome from which it is transcr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Royal Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936258/ https://www.ncbi.nlm.nih.gov/pubmed/31795917 http://dx.doi.org/10.1098/rsob.190213 |