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Sunitinib Does Not Accelerate Tumor Growth in Patients with Metastatic Renal Cell Carcinoma

Preclinical studies have suggested that sunitinib accelerates metastases in animals, ascribing this to inhibition of the vascular endothelial growth factor receptor or the tumor’s adaptation. To address whether sunitinib accelerates tumors in humans, we analyzed data from the pivotal randomized phas...

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Detalles Bibliográficos
Autores principales: Blagoev, Krastan B., Wilkerson, Julia, Stein, Wilfred D., Motzer, Robert J., Bates, Susan E., Fojo, A. Tito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936322/
https://www.ncbi.nlm.nih.gov/pubmed/23395639
http://dx.doi.org/10.1016/j.celrep.2013.01.015