Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma

Transcriptional profiling has defined pancreatic ductal adenocarcinoma (PDAC) into distinct subtypes with the majority being classical epithelial (E) or quasi-mesenchymal (QM). Despite clear differences in clinical behavior, growing evidence indicates these subtypes exist on a continuum with feature...

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Detalles Bibliográficos
Autores principales: Porter, Rebecca L., Magnus, Neelima K. C., Thapar, Vishal, Morris, Robert, Szabolcs, Annamaria, Neyaz, Azfar, Kulkarni, Anupriya S., Tai, Eric, Chougule, Abhijit, Hillis, Alissandra, Golczer, Gabriel, Guo, Hongshan, Yamada, Teppei, Kurokawa, Tomohiro, Yashaswini, Chittampalli, Ligorio, Matteo, Vo, Kevin D., Nieman, Linda, Liss, Andrew S., Deshpande, Vikram, Lawrence, Michael S., Maheswaran, Shyamala, Fernandez-Del Castillo, Carlos, Hong, Theodore S., Ryan, David P., O’Dwyer, Peter J., Drebin, Jeffrey A., Ferrone, Cristina R., Haber, Daniel A., Ting, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936349/
https://www.ncbi.nlm.nih.gov/pubmed/31843922
http://dx.doi.org/10.1073/pnas.1914915116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936349/
https://www.ncbi.nlm.nih.gov/pubmed/31843922
http://dx.doi.org/10.1073/pnas.1914915116

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