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Affinity maturation in a human humoral response to influenza hemagglutinin
Affinity maturation of the B cell antigen receptor (BCR) is a conserved and crucial component of the adaptive immune response. BCR lineages, inferred from paired heavy- and light-chain sequences of rearranged Ig genes from multiple descendants of the same naive B cell precursor (the lineages’ unmuta...
Autores principales: | McCarthy, Kevin R., Raymond, Donald D., Do, Khoi T., Schmidt, Aaron G., Harrison, Stephen C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936356/ https://www.ncbi.nlm.nih.gov/pubmed/31843892 http://dx.doi.org/10.1073/pnas.1915620116 |
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