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Spatial variations in gut permeability are linked to type 1 diabetes development in non-obese diabetic mice

OBJECTIVES: To determine if spatial variations in gut permeability play a role in regulating type 1 diabetes (T1D) progression. RESEARCH DESIGN AND METHODS: Spatially resolved duodenum, jejunum, ileum, and large intestine sections from end-stage T1D non-obese diabetic (NOD) mice were probed by immun...

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Detalles Bibliográficos
Autores principales: Joesten, William C, Short, Audrey H, Kennedy, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936454/
https://www.ncbi.nlm.nih.gov/pubmed/31908796
http://dx.doi.org/10.1136/bmjdrc-2019-000793