Cargando…

Spatial variations in gut permeability are linked to type 1 diabetes development in non-obese diabetic mice

OBJECTIVES: To determine if spatial variations in gut permeability play a role in regulating type 1 diabetes (T1D) progression. RESEARCH DESIGN AND METHODS: Spatially resolved duodenum, jejunum, ileum, and large intestine sections from end-stage T1D non-obese diabetic (NOD) mice were probed by immun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joesten, William C, Short, Audrey H, Kennedy, Michael A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Pathophysiology/Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936454/ https://www.ncbi.nlm.nih.gov/pubmed/31908796 http://dx.doi.org/10.1136/bmjdrc-2019-000793

Ejemplares similares

Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction
por: Yu, Fei, et al.
Publicado: (2020)

Contrast sensitivity to spatial gratings in moderate and dim light conditions in patients with diabetes in the absence of diabetic retinopathy
por: Safi, Sare, et al.
Publicado: (2017)

Spatial Patterns of Structural Brain Changes in Type 2 Diabetic Patients and Their Longitudinal Progression With Intensive Control of Blood Glucose
por: Erus, Guray, et al.
Publicado: (2015)

Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study
por: Jaiswal, Mamta, et al.
Publicado: (2017)

Glomerular filtration rate in patients with type 2 diabetes mellitus: is serum isthmin-1 level a possible link?
por: Xu, Mingyue, et al.
Publicado: (2023)

Nitric Oxide Bioavailability and Its Potential Relevance to the Variation in Susceptibility to the Renal and Vascular Complications in Patients With Type 2 Diabetes
por: Earle, Kenneth A., et al.
Publicado: (2009)

Variations in Risk of End-Stage Renal Disease and Risk of Mortality in an International Study of Patients With Type 1 Diabetes and Advanced Nephropathy
por: Skupien, Jan, et al.
Publicado: (2019)

Inflammation and Progressive Nephropathy in Type 1 Diabetes in the Diabetes Control and Complications Trial
por: Lin, Julie, et al.
Publicado: (2008)

Declining trends of diabetic nephropathy, retinopathy and neuropathy with improving diabetes care indicators in Japanese patients with type 2 and type 1 diabetes (JDDM 46)
por: Yokoyama, Hiroki, et al.
Publicado: (2018)

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes
por: Cousminer, Diana L., et al.
Publicado: (2018)

Glucose and C-Peptide Changes in the Perionset Period of Type 1 Diabetes in the Diabetes Prevention Trial–Type 1
por: Sosenko, Jay M., et al.
Publicado: (2008)

Association of fasting insulin and C peptide with diabetic retinopathy in Latinos with type 2 diabetes
por: Kuo, Jane Z, et al.
Publicado: (2014)

Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetes
por: Eriksson, Marika I, et al.
Publicado: (2021)

Cardiovascular autonomic neuropathy and the impact on progression of diabetic kidney disease in type 1 diabetes
por: Bjerre-Christensen, Theis, et al.
Publicado: (2021)

Clinical and biochemical profile of 786 sequential episodes of diabetic ketoacidosis in adults with type 1 and type 2 diabetes mellitus
por: Ooi, Emma, et al.
Publicado: (2021)

Serum Trypsinogen Levels in Type 1 Diabetes
por: Li, Xia, et al.
Publicado: (2017)

Systemic AAV10.COMP-Ang1 rescues renal glomeruli and pancreatic islets in type 2 diabetic mice
por: Tian, Mi, et al.
Publicado: (2020)

Insulin Gene Mutations as Cause of Diabetes in Children Negative for Five Type 1 Diabetes Autoantibodies
por: Bonfanti, Riccardo, et al.
Publicado: (2009)

Diminished Alveolar Microvascular Reserves in Type 2 Diabetes Reflect Systemic Microangiopathy
por: Chance, William W., et al.
Publicado: (2008)

In Vivo Insulin Sensitivity and Secretion in Obese Youth: What are the differences between normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes?
por: Bacha, Fida, et al.
Publicado: (2009)

Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial
por: Lachin, John M., et al.
Publicado: (2017)

Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns That Associate With Future Diabetic Complications
por: Schrader, Silja, et al.
Publicado: (2022)

Biomarkers of tubulointerstitial damage and function in type 1 diabetes
por: de Boer, Ian H, et al.
Publicado: (2017)

Visual impairment and mortality in patients with type 2 diabetes
por: Siersma, Volkert, et al.
Publicado: (2019)

Burden of Urological Complications in Men and Women With Long-standing Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Cohort
por: Wessells, Hunter, et al.
Publicado: (2018)

Impact of undiagnosed type 2 diabetes and pre-diabetes on severity and mortality for SARS-CoV-2 infection
por: Vargas-Vázquez, Arsenio, et al.
Publicado: (2021)

Associations between continuous glucose monitoring-derived metrics and diabetic retinopathy and albuminuria in patients with type 2 diabetes
por: Wakasugi, Satomi, et al.
Publicado: (2021)

Early choroidal changes detected by swept-source OCT in type 2 diabetes and their association with diabetic kidney disease
por: Da Silva, Monica Oliveira, et al.
Publicado: (2022)

Using in vivo corneal confocal microscopy to identify diabetic sensorimotor polyneuropathy risk profiles in patients with type 1 diabetes
por: Lewis, Evan J H, et al.
Publicado: (2017)

Association of diabetic retinopathy with both sarcopenia and muscle quality in patients with type 2 diabetes: a cross-sectional study
por: Fukuda, Tatsuya, et al.
Publicado: (2017)

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes
por: Sims, Emily K., et al.
Publicado: (2019)

Presentation, pathology and prognosis of renal disease in type 2 diabetes
por: Tan, Jasmine, et al.
Publicado: (2017)

Skin autofluorescence predicts cancer in subjects with type 2 diabetes
por: Foussard, Ninon, et al.
Publicado: (2021)

A1C Variability and the Risk of Microvascular Complications in Type 1 Diabetes: Data from the Diabetes Control and Complications Trial
por: Kilpatrick, Eric S., et al.
Publicado: (2008)

Prognostic Value of the Insertion/Deletion Polymorphism of the ACE Gene in Type 2 Diabetic Subjects: Results from the Non-Insulin-Dependent Diabetes, Hypertension, Microalbuminuria or Proteinuria, Cardiovascular Events, and Ramipril (DIABHYCAR), Diabete de type 2, Nephropathie et Genetique (DIAB2NEPHROGENE), and Survie, Diabete de type 2 et Genetique (SURDIAGENE) studies
por: Hadjadj, Samy, et al.
Publicado: (2008)

Insulin Administration and Rate of Glucose Appearance in People With Type 1 Diabetes
por: Pennant, Mary E., et al.
Publicado: (2008)

Retinal Arteriolar Dilation Predicts Retinopathy in Adolescents With Type 1 Diabetes
por: Cheung, Ning, et al.
Publicado: (2008)

Systemic inflammatory responses in patients with type 2 diabetes with chronic periodontitis
por: Mesia, Ruben, et al.
Publicado: (2016)

Hypoglycemia in patient with type 2 diabetes treated with insulin: it can happen
por: Heller, Simon R, et al.
Publicado: (2020)

Rod phototransduction and light signal transmission during type 2 diabetes
por: Becker, Silke, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7c4v38tsvjsnm4a39j0q4o260t