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Approaching infinite affinity through engineering of peptide–protein interaction

Much of life’s complexity depends upon contacts between proteins with precise affinity and specificity. The successful application of engineered proteins often depends on high-stability binding to their target. In recent years, various approaches have enabled proteins to form irreversible covalent i...

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Detalles Bibliográficos
Autores principales: Keeble, Anthony H., Turkki, Paula, Stokes, Samuel, Khairil Anuar, Irsyad N. A., Rahikainen, Rolle, Hytönen, Vesa P., Howarth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936558/
https://www.ncbi.nlm.nih.gov/pubmed/31822621
http://dx.doi.org/10.1073/pnas.1909653116