Cargando…

Viral neutralization by antibody-imposed physical disruption

In adaptive immunity, organisms produce neutralizing antibodies (nAbs) to eliminate invading pathogens. Here, we explored whether viral neutralization could be attained through the physical disruption of a virus upon nAb binding. We report the neutralization mechanism of a potent nAb 8C11 against th...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Qingbing, Jiang, Jie, He, Maozhou, Zheng, Zizheng, Yu, Hai, Li, Tingting, Xue, Wenhui, Tang, Zimin, Ying, Dong, Li, Zekai, Song, Shuo, Liu, Xinlin, Wang, Kaihang, Zhang, Zhiqing, Wang, Daning, Wang, Yingbin, Yan, Xiaodong, Zhao, Qinjian, Zhang, Jun, Gu, Ying, Li, Shaowei, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936700/
https://www.ncbi.nlm.nih.gov/pubmed/31818956
http://dx.doi.org/10.1073/pnas.1916028116