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Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis

BACKGROUND AND AIMS: Mesial Temporal Lobe Epilepsy is characterized by progressive changes of both neurons and glia, also referred to as epileptogenesis. No curative treatment options, apart from surgery, are available. DNA methylation (DNAm) is a potential upstream mechanism in epileptogenesis and...

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Detalles Bibliográficos
Autores principales: Berger, Toni C., Vigeland, Magnus D., Hjorthaug, Hanne S., Etholm, Lars, Nome, Cecilie G., Taubøll, Erik, Heuser, Kjell, Selmer, Kaja K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936816/
https://www.ncbi.nlm.nih.gov/pubmed/31887157
http://dx.doi.org/10.1371/journal.pone.0226575