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Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis
BACKGROUND AND AIMS: Mesial Temporal Lobe Epilepsy is characterized by progressive changes of both neurons and glia, also referred to as epileptogenesis. No curative treatment options, apart from surgery, are available. DNA methylation (DNAm) is a potential upstream mechanism in epileptogenesis and...
Autores principales: | Berger, Toni C., Vigeland, Magnus D., Hjorthaug, Hanne S., Etholm, Lars, Nome, Cecilie G., Taubøll, Erik, Heuser, Kjell, Selmer, Kaja K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936816/ https://www.ncbi.nlm.nih.gov/pubmed/31887157 http://dx.doi.org/10.1371/journal.pone.0226575 |
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