APOBEC3A is a prominent cytidine deaminase in breast cancer

APOBEC cytidine deaminases are the second-most prominent source of mutagenesis in sequenced tumors. Previous studies have proposed that APOBEC3B (A3B) is the major source of mutagenesis in breast cancer (BRCA). We show that APOBEC3A (A3A) is the only APOBEC whose expression correlates with APOBEC-in...

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Detalles Bibliográficos
Autores principales: Cortez, Luis M., Brown, Amber L., Dennis, Madeline A., Collins, Christopher D., Brown, Alexander J., Mitchell, Debra, Mertz, Tony M., Roberts, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936861/
https://www.ncbi.nlm.nih.gov/pubmed/31841499
http://dx.doi.org/10.1371/journal.pgen.1008545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936861/
https://www.ncbi.nlm.nih.gov/pubmed/31841499
http://dx.doi.org/10.1371/journal.pgen.1008545

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