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Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo

Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses. α-defensins are effector molecules of the innate immune response and have been shown to modulate natural infection with adenoviruses, but the majori...

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Detalles Bibliográficos
Autores principales: Tartaglia, Lawrence J., Badamchi-Zadeh, Alexander, Abbink, Peter, Blass, Eryn, Aid, Malika, Gebre, Makda S., Li, Zhenfeng, Pastores, Kevin Clyde, Trott, Sebastien, Gupte, Siddhant, Larocca, Rafael A., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936886/
https://www.ncbi.nlm.nih.gov/pubmed/31841560
http://dx.doi.org/10.1371/journal.ppat.1008180