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Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo
Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses. α-defensins are effector molecules of the innate immune response and have been shown to modulate natural infection with adenoviruses, but the majori...
Autores principales: | Tartaglia, Lawrence J., Badamchi-Zadeh, Alexander, Abbink, Peter, Blass, Eryn, Aid, Malika, Gebre, Makda S., Li, Zhenfeng, Pastores, Kevin Clyde, Trott, Sebastien, Gupte, Siddhant, Larocca, Rafael A., Barouch, Dan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936886/ https://www.ncbi.nlm.nih.gov/pubmed/31841560 http://dx.doi.org/10.1371/journal.ppat.1008180 |
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