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Improving the practicality of using non-aversive handling methods to reduce background stress and anxiety in laboratory mice
Handling can stimulate stress and anxiety in laboratory animals that negatively impacts welfare and introduces a confounding factor in many areas of research. Picking up mice by the tail is a major source of handling stress that results in strong aversion to the handler, while mice familiarised with...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937263/ https://www.ncbi.nlm.nih.gov/pubmed/31889107 http://dx.doi.org/10.1038/s41598-019-56860-7 |