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Butyrate attenuated fat gain through gut microbiota modulation in db/db mice following dapagliflozin treatment

We investigated the effect of a combination treatment with dapagliflozin (Dapa), a sodium-glucose cotransporter-2 inhibitor and butyrate on weight change in db/db mice. Six-week-old male db/db mice were assigned to four groups: vehicle with normal chow diet (NCD), Dapa with NCD, vehicle with 5% sodi...

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Detalles Bibliográficos
Autores principales: Oh, Tae Jung, Sul, Woo Jun, Oh, Han Na, Lee, Yun-Kyung, Lim, Hye Li, Choi, Sung Hee, Park, Kyong Soo, Jang, Hak Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937275/
https://www.ncbi.nlm.nih.gov/pubmed/31889105
http://dx.doi.org/10.1038/s41598-019-56684-5