Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy

Maternal or paternal high fat (HF) diet can modify the epigenome in germ cells and fetal somatic cells leading to an increased susceptibility among female offspring of multiple generations to develop breast cancer. We determined if combined treatment with broad spectrum DNA methyltransferase (DNMT)...

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Detalles Bibliográficos
Autores principales: Andrade, F. de Oliveira, Nguyen, N. M., Warri, A., Hilakivi-Clarke, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937280/
https://www.ncbi.nlm.nih.gov/pubmed/31889127
http://dx.doi.org/10.1038/s41598-019-56854-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937280/
https://www.ncbi.nlm.nih.gov/pubmed/31889127
http://dx.doi.org/10.1038/s41598-019-56854-5

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