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Transcriptomic changes during TGF-β-mediated differentiation of airway fibroblasts to myofibroblasts

Asthma is the most common chronic lung disease in children and young adults worldwide. Airway remodelling (including increased fibroblasts and myofibroblasts in airway walls due to chronic inflammation) differentiates asthmatic from non-asthmatic airways. The increase in airway fibroblasts and myofi...

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Detalles Bibliográficos
Autores principales: Walker, Erin Joanne, Heydet, Deborah, Veldre, Timothy, Ghildyal, Reena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937312/
https://www.ncbi.nlm.nih.gov/pubmed/31889146
http://dx.doi.org/10.1038/s41598-019-56955-1