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Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas

The vast majority of cervical and 75% of oropharyngeal carcinomas are triggered by infection with a type of high-risk oncogenic human papillomavirus (HPV). It is well-known that E6 and E7 oncoproteins are critical for viral-induced cancer, and hence, they represent valuable targets for therapeutic i...

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Detalles Bibliográficos
Autores principales: Senthilkumar, Rajendran, Brusentsev, Yury, Paul, Preethy, Marimuthu, Parthiban, Cheng, Fang, Eklund, Patrik C., Eriksson, John Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937315/
https://www.ncbi.nlm.nih.gov/pubmed/31889069
http://dx.doi.org/10.1038/s41598-019-56410-1